Using galaxy server

I recently came across galaxy server for genome sequence manipulation. While I do large scale computing, I myself have thought several times to create a web based tool for large scale sequence manipulation, that will be able to handle huge data files. My requirements would often be to subtract sequences from one file to another, fetch sequences from huge fasta file containing names from a list file, find duplicate triplicate sequences, find sequences of a certain length etc. I think the galaxy server provides many of that through a web server. The link is here